Formation of an 6α,14-epoxy-bridged isomorphinan, an unusual product from a substituted 6α,14-dihydroxymorphinan

DOI: 10.1002/jhet.5570310638

Source and publish data:

Journal of Heterocyclic Chemistry p. 1509 - 1511 (1994)

Update date:2022-08-05

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Authors:

Davis Davis

Nelson Nelson

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Article abstract of DOI:10.1002/jhet.5570310638

During alkylation of 3-O-benzyl-6α-naltrexol (1) with large aralkyl halides like 2-bromomethylnaphthalene and 9-chloromethylanthracene under phase transfer catalysis conditions (potassium hydroxide, tetrabutylammonium bromide, methylene chloride), formati

Full text of DOI:10.1002/jhet.5570310638

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