Formation of an 6α,14-epoxy-bridged isomorphinan, an unusual product from a substituted 6α,14-dihydroxymorphinan

DOI: 10.1002/jhet.5570310638

Source and publish data:

Journal of Heterocyclic Chemistry p. 1509 - 1511 (1994)

Update date:2022-08-05

Topics:

Authors:

Davis Davis

Nelson Nelson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570310638

During alkylation of 3-O-benzyl-6α-naltrexol (1) with large aralkyl halides like 2-bromomethylnaphthalene and 9-chloromethylanthracene under phase transfer catalysis conditions (potassium hydroxide, tetrabutylammonium bromide, methylene chloride), formati

Full text of DOI:10.1002/jhet.5570310638

Products guided by the article

Product name:17-cyclopropylmethyl-6α,14-epoxy-4,5α-epoxy-3-benzyloxymorphinan

Cas No:161199-69-5

R&D Labs maybe for 161199-69-5

Shanghai Hohance Chemical Co., ltd

Contact:13914753421

Address:Fl.5；Bld. 70, Lane 1500; Xinfei Road
Zhejiang Chemicals Import & Export Corporation

Contact:86-571-87043088

Address:No.37,Qingchun Road,Hangzhou,China
Disynthesis Chemical Technology Co. Ltd.

Contact:+86-571-88194596

Address:Dengyun road 380, Gongshu district, Hangzhou city, China
QINGDAO ON-BILLION INDUSTRAIL CO.,LTD

website:http://www.obn.com.cn

Contact:+86-15005320811 +86-532-80681989

Address:F35 Parkson Mansion No.44-60 Zhongshan Rd.
Zhejiang Linhai Xinhua Chemicals Factory

Contact:0086-13661858911

Address:Xunqiao Development Zone, Linhai, Zhejiang, China

Relevant to this article

Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c] pyrazoles as N-type calcium channel inhibitors

Doi:10.1016/j.bmcl.2014.03.063
(2014)
Catalyst-free microwave-assisted arylglyoxal-based multicomponent reactions for the synthesis of fused pyrans

Doi:10.1039/c5ra25536h
(2016)
Iron(III) sulfate as terminal oxidant in the synthesis of methyl ketones via wacker oxidation

Doi:10.1021/jo500921j
(2014)
Silver hexafluoroantimonate-catalyzed direct α-alkylation of unactivated ketones

Doi:10.1002/adsc.201400870
(2015)
Palladium-catalyzed α-arylation of aryloxyketones for the synthesis of 2,3-Disubstituted benzofurans

Doi:10.1021/jo500885w
(2014)
Nanomolar fluorogenic detection of Al(iii) by a series of Schiff bases in an aqueous system and their application in cell imaging

Doi:10.1039/c4ob00329b
(2014)

Article Doi