Tetrahedron Letters p. 381 - 382 (1995)
Update date:2022-08-04
Topics:
Gmeiner, Peter
Orecher, Florian
Thomas, Christoph
Weber, Klaus
Starting from the chiral building block 1, which is readily available from natural aspartic acid, a concise and versatile synthesis of optically active β-amino acids including β-proline derivatives is reported.Regioselective transformations of the 1,4-bis-electrophile 2 are facilitated by an anchimeric participation.
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