Ring contraction of cyclobutanes and a novel cascade reaction: Application to synthesis of (±)-anthoplalone and (±)-lepidozene

Article abstract of DOI:10.1021/jo00105a028

Two efficient and practical synthetic methodologies for the construction of small ring systems have been developed. The first method involves a novel rearrangement of cyclobutanes 10 and 14 leading to cyclopropanes 11 and 15 employing BF₃·OEt