Selenium-induced cyclization of O-allyl oximes as a synthetic route to N-alkyl isoxazolidines

DOI: 10.1016/0040-4020(94)01006-L

Source and publish data:

Tetrahedron p. 1277 - 1284 (1995)

Update date:2022-08-05

Topics:

Authors:

Tiecco, Marcello

Testaferri, Lorenzo

Tingoli, Marco

Bagnoli, Luana

Santi, Claudio

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Article abstract of DOI:10.1016/0040-4020(94)01006-L

Phenylselenyl bromide easily reacts with O-allyl oximes to afford cyclic iminium bromides which can be reduced in situ with sodium borohydride to produce substitued N-alkyl isoxazolidines in good yield.

Full text of DOI:10.1016/0040-4020(94)01006-L

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