Radical cyclization of α-allenic ketone: A new approach to the synthesis of (±)-α-chamigrene

Article abstract of DOI:10.1016/0040-4020(96)00785-5

A regioselective cyclization of ε-alkyl radicals attacking on the sp-carbon of α-allenic ketone to construct a spiro[5.5]undecane skeleton has been studied, and a new approach to the synthesis of (±)-α-chamigrene 22 is also reported.