Facile Synthesis of Optically Active anti-α,β-Dihydroxy Ester Derivatives

Article abstract of DOI:10.1246/cl.1990.1019

Anti-α,β-dihydroxy thioesters are prepared with excellent enantioselectivities by the asymmetric aldol reaction between both achiral aldehydes and silyl enol ethers derived from α-benzyloxy thioesters in the presence of a chiral promoter consisted of chir