Synthesis of 2'-Deoxynucleosid-3'-yl-N,N-Diisopropylaminophosphorfluoridites. A New Class of Stable PIII Nucleotides Containing a P-F Bond

DOI: 10.1016/0040-4039(94)02403-X

Source and publish data:

Tetrahedron Letters p. 1095 - 1098 (1995)

Update date:2022-08-05

Topics:

Authors:

Dabkowski, Wojciech

Tworowska, Izabela

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Article abstract of DOI:10.1016/0040-4039(94)02403-X

A new methodology based on phosphitylating reagents containing 4-nitrophenoxy leaving group has been employed to synthesize stable 5'-O-(4,4'-dimethoxytrityl)nucleosid-3'-yl-N,N-diisopropylaminophosphofluoridites 1a-d.

Full text of DOI:10.1016/0040-4039(94)02403-X

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