
Tetrahedron Letters p. 9717 - 9720 (1994)
Update date:2022-08-03
Topics:
Pulicani
Bezard
Bourzat
Bouchard
Zucco
Deprez
Commercon
A new route to semisynthetic 2-modified docetaxel analogs is described using electrochemical cleavage of the 2-benzoate as the key reaction. Subsequent reacylation at C-2 followed by sequential deprotections afforded the title analogs. Biological results
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(1996)