Unnatural amino acids increase activity and specificity of synthetic substrates for human and malarial cathepsin C

DOI: 10.1007/s00726-013-1654-2

Source and publish data:

Amino Acids p. 931 - 943 (2014)

Update date:2022-09-26

Topics:

Authors:

Poreba, Marcin

Mihelic, Marko

Krai, Priscilla

Rajkovic, Jelena

Krezel, Artur

Pawelczak, Malgorzata

Klemba, Michael

Turk, Dusan

Turk, Boris

Latajka, Rafal

Drag, Marcin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1007/s00726-013-1654-2

Mammalian cathepsin C is primarily responsible for the removal of N-terminal dipeptides and activation of several serine proteases in inflammatory or immune cells, while its malarial parasite ortholog dipeptidyl aminopeptidase 1 plays a crucial role in ca

Full text of DOI:10.1007/s00726-013-1654-2

Products guided by the article

Product name:NH₂-Met-Glu(Bzl)-(7-amino-4-carbamoylmethylcoumarin)

Cas No:1639394-80-1

R&D Labs maybe for 1639394-80-1

Tianjin Realet Chemical Technology Co.,Ltd.

website:http://www.realetchem.com

Contact:+86-022-58788819

Address:shuanggang industrial park
Chengdu Aslee Biopharmaceuticals, Inc

Contact:18608018419

Address:Chengdu Aslee Biopharmaceuticals, Inc
Xi'an Galaxy Chemicals CO., Ltd

Contact:86-29-89380370

Address:No.8, Gaoxin three road, Xi'an city.
zhejiang huangyan wanfeng pharm chem co.ltd

Contact:+86-576- 84160728

Address:No. 5 Dazha Road, Economic,Development Zone(JiangKou), Zhejiang, China
Hefei Lifeon Pharmaceutical Co., Ltd.

Contact:+86-551-65328450

Address:No522 Wangjiang West Road

Relevant to this article

Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: Altered alamethicin concentration and utility to screen for UGT inhibitors

Doi:10.1124/dmd.111.043117
(2012)
Discovery of novel antitumor sulfonamides targeting G1 phase of the cell cycle

Doi:10.1021/jm9902638
(1999)
Diastereoselective trifluoromethylation of chiral imide enolates with iodotrifluoromethane mediated by triethylborane

Doi:10.1016/0957-4166(94)80046-4
(1994)
Triphenylamine, carbazole or tetraphenylethylene-based gold(I) complexes: Tunable solid-state room-temperature phosphorescence and various mechanochromic luminescence characteristics

Doi:10.1016/j.dyepig.2018.07.016
(2018)
Doi:10.1007/BF01172568
()
A general preparation of β-substituted tryptophan esters

Doi:10.1016/0040-4039(95)00180-K
(1995)

Article Doi