Journal of Medicinal Chemistry p. 2714 - 2727 (1995)
Update date:2022-08-05
Topics:
Lakanen, John R.
Pegg, Anthony E.
Coward, James K.
The synthesis of a new class of multisubstrate adduct inhibitors of polyamine biosynthesis has been investigated.The first target compound, designed to inhibit spermidine synthase, was obtained and proved to be a very potent inhibitor of that enzyme.Two s
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