Synthesis of Optically Pure 1,4-Dihydropyridine Derivatives by Means of Diastereoisomeric Separation of the Hantzsch Intermediates Bearing (R)-1-Phenylethylamino Group

DOI: 10.3987/COM-94-S(B)51

Source and publish data:

Heterocycles p. 591 - 602 (1994)

Update date:2022-07-29

Topics:

Authors:

Kosugi, Yoshiyuki

Hori, Masanori

Nagasaka, Tatsuo

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Article abstract of DOI:10.3987/COM-94-S(B)51

Hantzsch intermediates, which were obtained by Michael addition reaction of benzylideneacetoacetates with the enamino esters bearing (R)-1-phenylethylamino group as a chiral auxiliary, were separated into two diastereoisomeric mixtures.Each of them underw

Full text of DOI:10.3987/COM-94-S(B)51

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