Synlett p. 1 - 10 (1997)
Update date:2022-08-04
Topics:
Wipf, Peter
Venkatraman, Srikanth
Since its isolation in 1991, the polyazole natural product thiangazole has become a popular target for total synthesis due to its challenging array of heterocyclic segments and its reported potent antiviral activity. The synthetic activity toward thiangazole is reviewed and a novel approach that takes advantage of aziridine and oxazoline intermediates en route to thiazolines is presented.
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