A SHORT SYNTHESIS OF ANTITUMOR ETHER THIOGLYCOLIPIDS: THIOGLYCOSIDATION OF A GLUCOSE DONOR WITH A TRIBUTYLSTANNYL SULFIDE ACCEPTOR

Article abstract of DOI:10.1016/0040-4039(95)01015-A

Efficient routes to α- and β-thioglucolipids 1a and 1b are described starting from 1-O-hexadecyl-3-O-(p-toluenesulfonyl)-sn-glycerol (2) in 72 percent and 68 percent overall yields, respectively.Deprotection of the S-benzyl group of the glyceride 4 with t