Journal of the Chemical Society. Perkin transactions I p. 471 - 474 (1987)
Update date:2022-07-30
Topics:
Arias, Jose M.
Breton, Jose L.
Gavin, Jose A.
Garcia-Granados, Andres
Martinez, Antonio
Onorato, M. Esther
Microbial transformation of the sesquiterpene lactone deoxyvulgarin (2) has been carried out with Aspergillus ochraceous and Rhizopus nigricans cultures.A. ochraceous converted deoxyvulgarin (2) into vulgarin (3) and 11,13-dihydrodouglanin (4).R. nigricans transformed deoxyvulgarin (2) into vulgarin (3), erivanin (6), and 1β-hydroxy-2-oxoeudesm-3-en-6,13-olide (7).Vulgarin (3) was obtained chemically by epoxidation of deoxyvulgarin (2) in one-step process in virtually quantitative yield.A pathway proposed for the conversion of deoxyvulgarin (2) into more functionalized metabolites is discussed.
View MoreHuangshan Honghui Pharm Technology Co., Ltd.(expird)
website:http://www.honghuichem.com
Contact:18855958372
Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province
Zhongshan Haihong Medicine Co., Ltd.
Contact:86-0760-86925778 （0）18824993998
Address:A7 building,lianyuan road Torch Hi-tech Industrial Development Zone
Longhui qunfeng Chemical Co., Ltd
Contact:86-731-82173407
Address:South-east Industrial Park, Longhui County, Hunan Province, China
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.
Contact:13861062998
Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Doi:10.1246/bcsj.70.965
(1997)Doi:10.1007/BF02219028
(1994)Doi:10.1002/asia.201100627
(2012)Doi:10.1021/ja00108a052
(1995)Doi:10.1016/0040-4020(95)00476-O
(1995)Doi:10.1016/0957-4166(95)00236-I
(1995)
