Neurosteroid analogues. 3. The synthesis and electrophysiological evaluation of benz[e]indene congeners of neuroactive steroids having the 5β- configuration

DOI: 10.1021/jm00022a021

Source and publish data:

Journal of Medicinal Chemistry p. 4548 - 4556 (1995)

Update date:2022-08-04

Topics:

Authors:

Han Han

Zorumski

Covey Covey

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00022a021

A series of 7-(2-hydroxyethyl)benz[e]indene analogues of 3α-hydroxy-5β- pregnan-20-one (7), a neuroactive steroid known to be a positive allosteric modulator of GABA(A) receptor function, was prepared. Electrophysiological measurements carried out on cult

Full text of DOI:10.1021/jm00022a021

Products guided by the article

Product name:<3S-(3α,3aα,5aβ,7β,9aα,9bβ)>-3-(1,1-dimethylethoxy)-dodecahydro-3a-methyl-N-<(S)-1-phenylethyl>-1H-benzindene-7-acetamide

Cas No:169952-42-5

R&D Labs maybe for 169952-42-5

Jinan Jiaquan Chemical Co.,Ltd

Contact:+86-531-62318366

Address:Room 502 of Yidonghuayuan No.601 Huaxin Road Licheng District Jinan China
GM CHMICAL CO., LTD

Contact:0086-21-80264647

Address:RM 202, NO 1602 West Zhongshan Rd, Shanghai, China
Hangzhou Share Chemical Co., Ltd(expird)

Contact:+86-57187093700

Address:Hang Xing Road
Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
BIOS CHEMICALS

Contact:+33-5-34012600

Address:28 ZA des Pignès

Relevant to this article

Rate Constants For F^- Transfer from SF6^- to Fluorinated Gases and SO2. Temperature Dependence and Implications or Electrical Discharges in SF6

Doi:10.1021/j100314a025
(1988)
Reaction of methyl 4,5-epoxy-(2E)-pentenoate with arenes. II. Application to the synthesis of(±)-curcudiol, (±)-curcuphenol, (±)-curcuhydroquinone, and(±)-curcuquinone

Doi:10.1248/cpb.43.553
(1995)
Structure-based design of parasitic protease inhibitors

Doi:10.1016/0968-0896(96)00136-8
(1996)
Glycerol electrooxidation in alkaline medium using Pd/c, Au/c and Pdau/c electrocatalysts prepared by electron beam irradiation

Doi:10.5935/0103-5053.20140044
(2014)
Metal Ion-Catalyzed Hydrolysis of Acrylate Esters and Amides by Way of Their Conjugate Addition Adducts

Doi:10.1021/jo00127a032
(1995)
Half-Sandwich Ruthenium Carbene Complexes Link trans-Hydrogenation and gem-Hydrogenation of Internal Alkynes

Doi:10.1021/jacs.8b00665
(2018)

Article Doi