Tetrahedron Letters p. 1075 - 1078 (1997)
Update date:2022-08-02
Topics:
Rosenthal, Katri
Karlstroem, Amelie
Unden, Anders
The 2,4-dimethylpent-3-yloxycarbonyl (Doc) group is presented as a new protecting group for tyrosine. The Doc group is 1000-fold more stable towards the nucleophile piperidine than the commonly used 2-bromobenzyloxycarbonyl (2-BrZ) group is, and it is completely cleaved by hydrogen fluoride.
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(1996)Doi:10.1021/jo9511197
(1996)Doi:10.1007/BF02333892
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(2019)Doi:10.1016/S0022-1139(00)80566-7
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