Tetrahedron Letters p. 779 - 782 (1997)
Update date:2022-08-03
Topics:
Neumann, William L.
Franklin, Gary W.
Sample, Kirby R.
Aston, Karl W.
Weiss, Randy H.
Riley, Dennis P.
A general method for the preparation of rigidified pentaazamacrocycles using trans-(1R,2R)-diaminocyclohexane as the conformational controller element. High macrocyclization yields have been obtained by strategic placement of the diamino-cyclohexane group within the pseudopeptide backbone.
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