Acylation of diethyl (ethoxycarbonyl)fluoromethylphosphonate using magnesium chloride-triethylamine: A facile synthesis of α-fluoro β-keto esters

DOI: 10.1016/0040-4039(95)02224-4

Source and publish data:

Tetrahedron Letters p. 653 - 654 (1996)

Update date:2022-08-03

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Authors:

Kim Kim

Rhie Rhie

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Article abstract of DOI:10.1016/0040-4039(95)02224-4

A facile synthesis of α-fluoro β-keto esters, via diacylation reaction of diethyl (ethoxycarbonyl)fluoromethylphosphonate with aromatic carboxylic acid chlorides in the presence of magnesium chloride-triethylamine followed by deacylation, is described.

Full text of DOI:10.1016/0040-4039(95)02224-4

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