Easy access to an enantiopure precursor of (+)-goniodiol

Article abstract of DOI:10.1016/0957-4166(96)00431-4

Asymmetric synthesis of the epoxide 2 has been achieved from (R)-mandelic acid 3 via highly diastereoselective Wittig reaction and erythro-selective OsO₄ catalyzed cis-hydroxylation as key steps. Copyright (C) Elsevier Science Ltd.