Nucleosides and Nucleotides p. 135 - 148 (1996)
Update date:2022-07-30
Topics:
Hancox, E. Louise
Walker, Richard T.
We report interesting and novel reactions of 4′-thionucleosides and their sulfone derivatives when a good leaving group is present in the 5′-position. The results have important implications for the phosphorylation of these nucleoside analogues by standard chemical procedures. Possible mechanisms for these reactions are discussed.
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