A facile and regio- and stereo-selective preparation of bicyclic guanidines by iodocyclization of 3-(alk-2-enyl)-2-(substituted amino)-1-imidazolin-4-ones

Article abstract of DOI:10.1016/0040-4020(96)00004-X

The iodocyclization of 3-(alk-2-enyl)-2-(substituted amino)-1-imidazolin-4-ones proceeded in regio- and stereo-selective manners to give bicyclic guanidines, imidazo[1,2-a]imidazole and/or imidazo[1,2-a]pyrimidine, in good yields. The regiochemistry of th