Tetrahedron Letters p. 1363 - 1366 (1996)
Update date:2022-08-03
Topics:
Banik, Bimal K.
Subbaraju, Gottumukkala V.
Manhas, Maghar S.
Bose, Ajay K.
Easy access to fused tricyclic β-lactams starting with o-bromobenzaldehyde and allyl amine has been devised using intramolecular aryl radical cyclization under the influence of tributyltin hydride. The major product resulted from exo cyclization leading to the formation of a 6-membered ring and thus a tricyclic β-lactam. In some cases, a minor product was a 7-membered ring-containing tricyclic β-lactam formed by endo cyclization.
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Doi:10.1021/ja953893h
(1996)Doi:10.1021/jo01045a040
(1963)Doi:10.1007/BF02434888
()Doi:10.1246/bcsj.64.1332
(1991)Doi:10.1021/jo980088n
(1999)Doi:10.1016/0022-328X(95)06085-B
(1996)
