Stereoselective synthesis of 2-aminoethyl substituted tricycles with NMDA receptor affinity

DOI: 10.1016/0957-4166(95)00190-Z

Source and publish data:

Tetrahedron Asymmetry p. 1527 - 1530 (1995)

Update date:2022-08-04

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Authors:

Wunsch Wunsch

Diekmann

Hofner Hofner

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Article abstract of DOI:10.1016/0957-4166(95)00190-Z

In this paper the stereoselective synthesis of the novel noncompetitive NMDA antagonist 15 with a k(i) value of 16.1 μM for the phencyclidine binding site is described. Key steps in the preparation of the tricycle 15 are the regio- and stereoselective for

Full text of DOI:10.1016/0957-4166(95)00190-Z

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