Preparation of 3'-phosphonate analogs of 2',3'-dideoxynucleosides

DOI: 10.1016/0040-4039(96)00829-5

Source and publish data:

Tetrahedron Letters p. 4297 - 4300 (1996)

Update date:2022-08-06

Topics:

Authors:

Lau Lau

Zhang Zhang

Wang Wang

Cheng Cheng

Zhao Zhao

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Article abstract of DOI:10.1016/0040-4039(96)00829-5

γ-Hydroxyl vinylphosphonate (6) has been efficiently prepared by the base-catalyzed opening of the readily available epoxide (5) and converted to the corresponding nucleosides for antiviral studies.

Full text of DOI:10.1016/0040-4039(96)00829-5

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