The catalytic Friedel-Crafts acylation reaction of aromatic compounds with carboxylic anhydrides using combined catalyst system of titanium(IV) chloride tris(trifluoromethanesulfonate) and trifluoromethanesulfonic acid

DOI: 10.1246/cl.1996.739

Source and publish data:

Chemistry Letters p. 739 - 740 (1996)

Update date:2022-07-30

Topics:

Authors:

Izumi, Jun

Mukaiyama, Teruaki

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Various aromatic ketones are prepared in good to high yields with carboxylic anhydrides using combined catalyst system of TiCl(OTf)₃ and TfOH.

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