Reactions of 3H-1,2-benzodithiol-3-one 1-oxide with amines and anilines

Article abstract of DOI:10.1016/0040-4039(96)01124-0

Reaction of 3H-1,2-benzodithiol-3-one 1-oxide with primary amines or anilines provides reasonable yields (40-70%) of the corresponding 1,2-benzisothiazolin-3(2H)-ones. These reactions may have relevance to the biological chemistry of 1,2-dithiolan-3-one 1-oxides and also offer a new method for the preparation of certain 1,2-benzisothiazolin-3(2H)-ones.