The synthesis and high-resolution NMR spectroscopy of ethyl N-(2-triphenylmethylthio)ethanoyl-O-{4′-[4″-(1″-bis(2?- chloroethyl)amino)phenyl]butanoyl}-L-seryl-S-benzyl-L-cysteine: A chelate-chlorambucil complex for use as a ligand for 99mTc rad

DOI: 10.1139/v96-167

Source and publish data:

Canadian Journal of Chemistry p. 1502 - 1511 (1996)

Update date:2022-08-03

Topics:

Authors:

Bell, Russell A.

Hughes, Donald W.

Lock, Colin J.L.

Valliant, John F.

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Article abstract of DOI:10.1139/v96-167

A potential agent for the imaging of tumours has been synthesized from the antineoplastic agent chlorambucil. Standard peptide coupling techniques were used to synthesize a tripeptide covalently coupled to chlorambucil in 10 steps. The final product was c

Full text of DOI:10.1139/v96-167

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