Tetrahedron Letters p. 6965 - 6968 (1996)
Update date:2022-08-03
Topics:
Wright, Stephen W.
Dow, Robert L.
McClure, Lester D.
Hageman, David L.
A synthetic approach to a structurally novel series of indoline 2,2-biscarboxylates is described that employs a tandem bis-alkylation strategy to cyclize the indoline heteroring from the bromide 7 and diethyl bromomalonate. The indolines thus prepared may be N-deprotected and further functionalized on the indoline nitrogen.
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(2000)
