Synthesis of dolastatin G and nordolastatin G, cytotoxic 35-membered cyclodepsipeptides of marine origin

Article abstract of DOI:10.1016/0040-4039(96)01653-X

The synthesis of dolastatin G (1) and nordolastatin G (2), new cytotoxic cyclodepsipeptides from the Japanese sea hare Dolabella auricularia, was achieved enantioselectively, and the present result confirmed their stereostructures unambiguously.