Synthesis of Macarpine and its Cytotoxicity: Toward a Synthetic Route for 12-Alkoxybenzophenanthridine Alkaloids through Aromatic Nitrosation under Basic Condition

DOI: 10.1016/0040-4020(95)00460-P

Source and publish data:

Tetrahedron p. 8447 - 8458 (1995)

Update date:2022-08-04

Topics:

Authors:

Ishikawa, Tsutomu

Saito, Tatsuru

Ishii, Hisashi

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Article abstract of DOI:10.1016/0040-4020(95)00460-P

Macarpine (1), a 2,3,7,8,10,12-hexaoxygenated benzophenanthridine alkaloid (O6 base), was effectively synthesized from sesamol methyl ether (7) through the newly developed aromatic nitrosation under basic condition.The tests for the cytotoxicity of 1 a

Full text of DOI:10.1016/0040-4020(95)00460-P

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