A new radical route to C4-unsubstituted β-lactams

DOI: 10.1016/S0040-4039(97)10476-2

Source and publish data:

Tetrahedron Letters p. 163 - 166 (1998)

Update date:2022-08-03

Topics:

Authors:

Alcaide, Benito

Rodriguez-Vicente, Alberto

Sierra, Miguel A.

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Article abstract of DOI:10.1016/S0040-4039(97)10476-2

C4-Unsubstituted β-lactams 3 are conveniently prepared from easily available 4-formyl-β-lactams 1, in a sequential three step synthesis, using as the key step a radical reductive decarbonylation of 4-carboxy derivatives through their phenyl selenoesters 2.

Full text of DOI:10.1016/S0040-4039(97)10476-2

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