Synthesis of A Modified Carboxylate-binding Pocket of Vancomycin

DOI: 10.1016/00404-0399(50)08649-

Source and publish data:

Tetrahedron Letters p. 4781 - 4784 (1995)

Update date:2022-07-29

Topics:

Authors:

Bois-Choussy, Michele

Beugelmans, Rene

Bouillon, Jean-Philippe

Zhu, Jieping

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Article abstract of DOI:10.1016/00404-0399(50)08649-

A 16-membered tetrapeptidic macrocycle (4), analog of vancomycin binding pocket, has been designated and synthesized using the efficient macrocyclisation of the corresponding linear tetrapeptide (14) via biaryl ether formation.In aceton, compound 4 adopte

Full text of DOI:10.1016/00404-0399(50)08649-

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