New synthetic method of 5-formyluracil-containing oligonucleotides and their melting behavior

DOI: 10.1016/S0040-4039(96)02130-2

Source and publish data:

Tetrahedron Letters p. 9067 - 9070 (1996)

Update date:2022-07-29

Topics:

Authors:

Sugiyama, Hiroshi

Matsuda, Shigeo

Kino, Katsuhito

Zhang, Qiu-Mei

Yonei, Shuji

Saito, Isao

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Article abstract of DOI:10.1016/S0040-4039(96)02130-2

A new method for the synthesis of 5-foU-containing oligonucleotides by phosphoramidite chemistry and subsequent post-oxidation with sodium periodate was developed. 5-(1,2-Dihydroxyethyl)uracil-containing oligomers, which are readily converted to 5-foU-con

Full text of DOI:10.1016/S0040-4039(96)02130-2

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Product name:5'-O-(4,4'-dimethoxytrityl)-5-(1,2-diacetoxyethyl)-2'-deoxyuridine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

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