Sugar-derived Ras inhibitors: Group epitope mapping by NMR spectroscopy and biological evaluation

DOI: 10.1002/ejoc.200600132

Source and publish data:

European Journal of Organic Chemistry p. 3707 - 3720 (2006)

Update date:2022-07-30

Topics:

Authors:

Peri, Francesco

Airoldi, Cristina

Colombo, Sonia

Mari, Silvia

Jimenez-Barbero, Jesus

Martegani, Enzo

Nicotra, Francesco

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Article abstract of DOI:10.1002/ejoc.200600132

Novel inhibitors of Ras protein activation have been found, containing a bicyclic core derived from D-arabinose and benzyl and phenylhydroxylamine moieties. NMR studies (trNOE, saturation-transfer difference, STD) of the binding between these molecules an

Full text of DOI:10.1002/ejoc.200600132

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