Alkyl 2-(2-Benzoyl-2-ethoxycarbonyl-1-ethenyl)amino-3dimethylaminopropenoates in the Synthesis of Heterocyclic Systems

Article abstract of DOI:10.1002/jhet.5570340139

Alkyl 2-(2-benzoyl-2-ethoxycarbonyl-1-ethenyl)amino-3-dimethylaminopropenoates 4a,b were prepared. They react with C-nucleophiles such a 2-pyridinylacetonitrile 5 and methyl-2-quinolinylacetate 8, cyclohexane-1,3-dione 10 and its derivatives 12 and 14, resorcinol derivative 16, 2-naphtol 18, 2-pyranone derivatives 20 and 22, and 4-hydroxypyridin-2(1H)-one 24, to form substituted amino derivatives of quinolizine 6, benzo[c]quinolizine 9, tetrahydrobenzopyran-2-one 11, 13, 15, naphto[2,1-b]pyran-3-one 19, pyranopyranones 21, 23, and pyrano[3,2-c]pyridine 25.