Bulletin of the Chemical Society of Japan p. 1067 - 1070 (1987)
Update date:2022-08-05
Topics:
Sakai, Takashi
Yamawaki, Akitoshi
Katayama, Tsuyoshi
Okada, Hiroshi
Utaka, Masanori
Takeda, Akira
Reaction of aromatic aldehydes or hetero-aromatic aldehydes with 3-chloro-3-methyl-2-butanone in ethanolic KOH at room temperature gave 3,3-dimethyl-5-aryltetrahydro-2-furanone as a major product.The reaction can be tentatively explained by the combination of Favorskii rearrangement and aldol reaction.
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