
Tetrahedron Letters p. 5963 - 5966 (1995)
Update date:2022-08-04
Topics:
Bastiaans, Harold M. M.
Van Der Baan, Juul L.
Ottenheijm, Harry C. J.
A flexible, convergent synthesis of cyclotheonamide B (1b) was developed, starting from the constituent amino acids, using conventional benzyl-, t-butyl- and allyl-based protecting groups. By modification of the key intermediates, this approach allows the preparation of cyclotheonamide analogues.
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