Synthesis of a novel fused tricyclic quinolone system via oxidation of 1,2,3,4-tetrahydro-β-carbolines

DOI: 10.1016/S0040-4039(97)00542-X

Source and publish data:

Tetrahedron Letters p. 2997 - 3000 (1997)

Update date:2022-08-03

Topics:

Authors:

Carniaux, Jean-Francois

Kan-Fan, Christiane

Royer, Jacques

Husson, Henri-Philippe

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Article abstract of DOI:10.1016/S0040-4039(97)00542-X

The new pyrrolo[3,4-b]quinolin-9-one system has been synthesized via metachloroperbenzoic acid oxidation of quinolones 5 and 10. These latter compounds were obtained by O₂ oxidation of 1,2,3,4-tetrahydro-β-carbolines. The unexpected m-CPBA oxidation has been studied in connection with the Polonovski reaction.

Full text of DOI:10.1016/S0040-4039(97)00542-X

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