Inhibition of peptidylglycine α-amidating monooxygenase by N-substituted homocysteine analogs

DOI: 10.1021/jm00052a002

Source and publish data:

Journal of Medicinal Chemistry p. 4430 - 4437 (1994)

Update date:2022-09-26

Topics:

Authors:

Erion Erion

Tan Tan

Wong Wong

Jeng Jeng

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00052a002

C-terminal amidation is a posttranslational modification found in many neuropeptides. Peptidylglycine α-amidating monooxygenase (PAM) catalyzes the synthesis of the biologically essential C-terminal amide from a glycine- extended precursor peptide. Report

Full text of DOI:10.1021/jm00052a002

Products guided by the article

Product name:[(S)-1-(2-Oxo-tetrahydro-thiophen-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester

Cas No:192310-93-3

R&D Labs maybe for 192310-93-3

Shanghai Puda Chemical Co.,Ltd

Contact:+86+571+56565965

Address:10F Haiyue Building,Danfeng Road,Binjiang District,Hangzhou,China
Lonzeal Pharmaceuticals Co., Ltd.

website:http://www.lonzeal.com

Contact:+86-13381011962

Address:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China
Landz International Company Ltd.

Contact:0086-21-58891610

Address:985 Dongfang Road, Pudong, Shanghai 200122 China
Geen Chemical Technology Co., Ltd

Contact:86-769-21660847

Address:1408, Yingfeng Commercial Center, Nancheng District
Qingdao XinYongAn Chemicals Co., Ltd

Contact:+86-532-81107967

Address:Chengyang dual-port industrial park by the sea，Qingdao

Relevant to this article

Doi:10.1016/S0040-4020(01)98664-8
(1968)
Polyurethanes containing boron chromophores as sidechains for nonlinear optics

Doi:10.1016/S0009-2614(97)88019-0
(1997)
Cationic aluminum alkyl complexes incorporating amidinate ligands. Transition-metal-free ethylene polymerization catalysts

Doi:10.1021/ja971815j
(1997)
Doi:10.1039/DT9780000877
()
Process design and scale-up of the synthesis of 2,2′:5′,2′-terthienyl

Doi:10.1021/op020044n
(2003)
Copper-Mediated [3+2] Annulation of 3-N-Hydroxyallylamines with Nitrosoarenes

Doi:10.1002/chem.201504784
(2016)

Article Doi