Inhibition of peptidylglycine α-amidating monooxygenase by N-substituted homocysteine analogs

DOI: 10.1021/jm00052a002

Source and publish data:

Journal of Medicinal Chemistry p. 4430 - 4437 (1994)

Update date:2022-09-26

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Authors:

Erion Erion

Tan Tan

Wong Wong

Jeng Jeng

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Article abstract of DOI:10.1021/jm00052a002

C-terminal amidation is a posttranslational modification found in many neuropeptides. Peptidylglycine α-amidating monooxygenase (PAM) catalyzes the synthesis of the biologically essential C-terminal amide from a glycine- extended precursor peptide. Report

Full text of DOI:10.1021/jm00052a002

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