Bioorganic and medicinal chemistry letters p. 3595 - 3598 (1998)
Update date:2022-08-04
Topics:
Adamczyk
Fishpaugh
Mattingly
Shreder
The synthesis, conjugation, and chemiluminescent evaluation of zero, first, and second order acridinium-based Tracermer signal generators are described. Members of this family of labels have potential use as tracers in diagnostic assays and are structurally similar to arborol dendrimers. Tracermer-BSA conjugates showed up to a sixfold increase in light emission compared to the normal acridinium label.
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Doi:10.1021/ja01591a027
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