Studies on the Chemistry of O,N- and S,N-Containing Heterocycles. 16 [1]. Investigations on the Synthesis of New Tricyclic β-Lactams via [2+2]Cycloaddition Reaction

Article abstract of DOI:10.1002/jhet.5570340319

Starting from methylthioimidates 1-8 a series of corresponding tricyclic β-lactams was synthesized via [2+2]cycloaddition with ketenes generated in situ from substituted acetyl chlorides. Dependent on the bicyclic starting material and on the substituent