Synthesis and antibacterial evaluation of [1,3]benzothiazino[3,2-a]quinoline- and [3,1]benzothiazino[1,2-a]quinoline-6-carboxylic acid derivatives

Article abstract of DOI:10.1016/S0968-0896(97)00084-9

A series of [1,3]benzothiazino[3,2-a]quinoline- (5) and [3,1]benzothiazino[l,2-a]quinoline-6-carboxylic acids (10) were synthesized and evaluated for their in vitro antibacterial activity. The activity is discussed in terms of their structural features re