The structural requirement of phosphatidylinositols as substrate of phosphatidylinositol 3-kinase

DOI: 10.1016/S0040-4039(99)00004-0

Source and publish data:

Tetrahedron Letters p. 1693 - 1696 (1999)

Update date:2022-08-04

Topics:

Authors:

Shirai, Ryuichi

Morita, Koji

Nishikawa, Asuka

Nakatsu, Noriyuki

Fukui, Yasuhisa

Morisaki, Naoko

Hashimoto, Yuichi

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Article abstract of DOI:10.1016/S0040-4039(99)00004-0

Synthetic distearate phosphatidylinositol (PI) was not phosphorylated by PI 3-kinase. The fatty acids at glycerol sn-2 must be as short as octanoic acid or less to act as a substrate of PI 3-kinase.

Full text of DOI:10.1016/S0040-4039(99)00004-0

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