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The structural requirement of phosphatidylinositols as substrate of phosphatidylinositol 3-kinase

DOI: 10.1016/S0040-4039(99)00004-0

Source and publish data:

Tetrahedron Letters p. 1693 - 1696 (1999)

Update date:2022-08-04

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Authors:

Shirai, RyuichiShirai, Ryuichi

Morita, KojiMorita, Koji

Nishikawa, AsukaNishikawa, Asuka

Nakatsu, NoriyukiNakatsu, Noriyuki

Fukui, YasuhisaFukui, Yasuhisa

Morisaki, NaokoMorisaki, Naoko

Hashimoto, YuichiHashimoto, Yuichi

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Article abstract of DOI:10.1016/S0040-4039(99)00004-0

Synthetic distearate phosphatidylinositol (PI) was not phosphorylated by PI 3-kinase. The fatty acids at glycerol sn-2 must be as short as octanoic acid or less to act as a substrate of PI 3-kinase.

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Full text of DOI:10.1016/S0040-4039(99)00004-0

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Product name:Octadecanoic acid (R)-2-[benzyloxy-((1S,2R,3R,4S,5S,6R)-2,6-bis-benzyloxymethoxy-3,4,5-trihydroxy-cyclohexyloxy)-phosphoryloxy]-1-octadecanoyloxymethyl-ethyl ester

Cas No:195970-38-8

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