Tetrahedron p. 12755 - 12764 (1997)
Update date:2022-07-30
Topics:
Ezquerra, Jesus
Lamas, Carlos
Pastor, Alfredo
Garcia-Navio, Jose L.
Vaquero, Juan J.
The Suzuki-type cross-coupling reaction of 6-substituted 1-benzyl-2-iodo-1H-benzimidazoles with aryl boronic acids provided an efficient synthesis of the corresponding 2-ary-1H-benzimidazoles. The reaction was catalyzed by palladium(0) under different conditions depending on the aryl group substitution.
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