
Synlett p. 1167 - 1170 (1997)
Update date:2022-08-04
Topics:
Sas
De Clercq
Vandewalle
1α,25-Dihydroxy-18-norvitamin D3 2a has been synthesized via two routes. In the first one, the CD-ring fragment 3 was obtained by an intermolecular Diels-Alder reaction via a decalin intermediate and subsequent ring contraction. The second approach is based on an intramolecular Diels-Alder reaction of a preconstructed nonatriene 8.
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Doi:10.1007/PL00011294
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(2016)