Synthesis and biological evaluation of 2',3'-dideoxy-3'-fluororibofuranosyl purine nucleosides

Article abstract of DOI:10.1080/07328319708006137

Synthesis of 9-(2,3-dideoxy-3-fluoro-β-D-ribofuranosyl)-2-chloroadenine (7b) and -2-chloro-6-methoxypurine (9b), as well as the α-D-anomer 7a of the former and its N⁷ isomer 10a is reported. Among the compounds synthesized, only the α-D-anomer

Full text of DOI:10.1080/07328319708006137

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Nucleosides and Nucleotides
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Synthesis and Biological Evaluation of
2′,3′-Dideoxy-3′-Fluororibofuranosyl
Purine Nucleosides
Nicolai E. Poopeiko a , Natalia B. Khripach a , Zygmunt
Kazimierczuk b , Jan Balzarini c , Erik De Clercq a & Igor A.
Mikhailopulo a
a Institute of Bioorganic Chemistry, Byelorussian Academy of
Sciences , 220141, Minsk, Byelorussia
b Institute of Experimental Physics, University of Warsaw ,
02-089, Warsaw, Poland
c Rega Institute for Medical Research, Katholieke Universiteit
Leuven , B-3000, Leuven, Belgium
Published online: 16 Aug 2006.
To cite this article: Nicolai E. Poopeiko , Natalia B. Khripach , Zygmunt Kazimierczuk , Jan
Balzarini , Erik De Clercq & Igor A. Mikhailopulo (1997) Synthesis and Biological Evaluation of
2′,3′-Dideoxy-3′-Fluororibofuranosyl Purine Nucleosides, Nucleosides and Nucleotides, 16:7-9,
1083-1086, DOI: 10.1080/07328319708006137
To link to this article: http://dx.doi.org/10.1080/07328319708006137
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