A facile synthesis of the 4-aza-analogs of 1-arylnaphthalene lignans chinensin, justicidin B, and Taiwanin C

DOI: 10.1016/S0040-4039(97)10204-0

Source and publish data:

Tetrahedron Letters p. 8295 - 8296 (1997)

Update date:2022-08-05

Topics:

Authors:

Hitotsuyanagi, Yukio

Kobayashi, Masatsugu

Fukuyo, Masamoto

Takeya, Koichi

Itokawa, Hideji

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Article abstract of DOI:10.1016/S0040-4039(97)10204-0

Reaction of anilines 1a-d with retronic acid (2) or 1,3- cyclopentanedione (3) produced anilinolactones 4a-d and anilinocyclopentenone 5a, respectively, which were then condensed with benzaldehydes to yield 4- aza-1-arylnaphthalene lignan analogs 6-19.

Full text of DOI:10.1016/S0040-4039(97)10204-0

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Product name:9-(3,4,5-Trimethoxy-phenyl)-6,7-dihydro-1,3-dioxa-5-aza-dicyclopenta[b,g]naphthalen-8-one

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