Journal of Organic Chemistry p. 1340 - 1347 (2018)
Update date:2022-08-03
Topics:
Maiti, Saikat
Mal, Prasenjit
In iodine(III)-catalyzed, dehydrogenative arylations of sulfonanilides, the functionalization of C-C bonds is preferred over the functionalization of C-N bonds. Herein, an unprecedented N-selective arylation of sulfonanilides using soft-hard acid-base (SHAB) control by a nitrenium ion over a carbenium ion is reported. Treatment of sulfonanilides with iodine(III) led to the formation of nitrenium ions (soft), which preferentially react with biphenyls (soft) over bimesityl (hard) to generate C-N bonds. The iodine(III) was generated in situ by using PhI and mCPBA at room temperature.
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Doi:10.1016/j.bmcl.2009.02.066
(2009)Doi:10.1016/j.tetlet.2004.04.190
(2004)Doi:10.1021/jm9600104
(1996)Doi:10.3987/com-98-8102
(1998)Doi:10.1021/jo01260a041
(1969)Doi:10.1016/S0040-4020(97)10267-8
(1998)