A convenient one-pot synthesis of 6-trifluoromethyl-pyridines

DOI: 10.3987/com-98-8102

Source and publish data:

Heterocycles p. 779 - 785 (1998)

Update date:2022-08-03

Topics:

Authors:

Katsuyama, Isamu

Ogawa, Seiya

Nakamura, Hiroko

Yamaguchi, Yoshihiro

Funabiki, Kazumasa

Matsui, Masaki

Muramatsu, Hiroshige

Shibata, Katsuyoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/com-98-8102

α,β-Unsaturated trifluoromethyl ketones (1) react with primary enamines (2) such as β-aminocrotononitrile and β-aminocrotonates in the presence of phosphorus oxychloride / pyridine adsorbed on silica gel and manganese dioxide, providing good to high yield

Full text of DOI:10.3987/com-98-8102

Products guided by the article

Product name:3-cyano-1,4-dihydro-2-methyl-4-phenyl-6-trifluoromethylpyridine

Cas No:200879-84-1

R&D Labs maybe for 200879-84-1

Zhejiang Haizhou Pharmaceutical Co., Ltd.

website:https://www.haizhoupharma.com/

Contact:+86-576-88221016

Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Nanjing Habo Medical Technology Co., Ltd.

Contact:025－85769882

Address:No.108. Ganjiabian east. Qixia District .Nanjing
Linhai East Way IMPORT&EXPORT CO.,Ltd

Contact:86-576-85285680

Address:81st,Shuiyun Nan Road
Hangzhou Mole's Science & Technology Co.,Ltd.(expird)

Contact:+86-571-56880228

Address:15F Guodu development Building, NO.182 Zhaohui Road
Zhuzhou Farshine Chemical Industry Co., Ltd

Contact:0086-731-28482786

Address:No. 1,Shui Xian Road, He Tang Dictrict,Hunan-412000,China

Relevant to this article

Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors

Doi:10.1021/jm4007774
(2013)
Enzymatic reduction of acetophenone derivatives with a benzil reductase from Pichia glucozyma (KRED1-Pglu): electronic and steric effects on activity and enantioselectivity

Doi:10.1039/c6ob00047a
(2016)
Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)- 1-phenylethanol derivatives

Doi:10.1016/j.ejmech.2012.01.034
(2012)
REACTION OF BENZYL CHLORIDE WITH PROPYLENE AND TRIFLUOROPROPENE UNDER METALLOCOMPLEX INITIATION CONDITIONS

Doi:10.1007/BF00961302
(1991)
On the Lewis acid-catalysed reaction of the 2,3-bis(trimethylstannyl)-1-alkene moiety with aldehydes

Doi:10.1016/0022-328X(91)86010-N
(1991)
β,β,β-Trichloroethyl-NH-Enamine as Viable System for 5-Endo-trig Radical Cyclization via Multifaceted Cu^I?Cu^II Redox Catalysis: Single Step Synthesis of Multi-Functionalized NH-Pyrroles

Doi:10.1002/adsc.201900938
(2019)

Article Doi