A convenient one-pot synthesis of 6-trifluoromethyl-pyridines

DOI: 10.3987/com-98-8102

Source and publish data:

Heterocycles p. 779 - 785 (1998)

Update date:2022-08-03

Topics:

Authors:

Katsuyama, Isamu

Ogawa, Seiya

Nakamura, Hiroko

Yamaguchi, Yoshihiro

Funabiki, Kazumasa

Matsui, Masaki

Muramatsu, Hiroshige

Shibata, Katsuyoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/com-98-8102

α,β-Unsaturated trifluoromethyl ketones (1) react with primary enamines (2) such as β-aminocrotononitrile and β-aminocrotonates in the presence of phosphorus oxychloride / pyridine adsorbed on silica gel and manganese dioxide, providing good to high yield

Full text of DOI:10.3987/com-98-8102

Products guided by the article

Product name:3-cyano-1,4-dihydro-2-methyl-4-phenyl-6-trifluoromethylpyridine

Cas No:200879-84-1

R&D Labs maybe for 200879-84-1

SHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.

website:http://www.tychemical.com

Contact:0086-358-3521713 3521715

Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China
Xiamen Huasing Chemicals Co.Ltd.

Contact:0086-592-6228397

Address:NO.24, Xinglin North 2nd Road,Jimei district
Shanghai PuYi Chem-Tech Co.,Ltd.

Contact:+86-21-57687505-227

Address:3 Floor, Building 11, No 201 MinYi Road, Songjiang District, Shanghai 201612, China
Jewim Pharmaceutical (Shandong) Co., Ltd

Contact:+8615621883869

Address:山东省泰安市高新技术产业开发区配天门大街西首
Beijing Cooperate Pharmaceutical Co.,Ltd

website:http://www.cooperate-pharm.com/

Contact:86-01060279497

Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base

Relevant to this article

Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors

Doi:10.1021/jm4007774
(2013)
Enzymatic reduction of acetophenone derivatives with a benzil reductase from Pichia glucozyma (KRED1-Pglu): electronic and steric effects on activity and enantioselectivity

Doi:10.1039/c6ob00047a
(2016)
Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)- 1-phenylethanol derivatives

Doi:10.1016/j.ejmech.2012.01.034
(2012)
REACTION OF BENZYL CHLORIDE WITH PROPYLENE AND TRIFLUOROPROPENE UNDER METALLOCOMPLEX INITIATION CONDITIONS

Doi:10.1007/BF00961302
(1991)
On the Lewis acid-catalysed reaction of the 2,3-bis(trimethylstannyl)-1-alkene moiety with aldehydes

Doi:10.1016/0022-328X(91)86010-N
(1991)
β,β,β-Trichloroethyl-NH-Enamine as Viable System for 5-Endo-trig Radical Cyclization via Multifaceted Cu^I?Cu^II Redox Catalysis: Single Step Synthesis of Multi-Functionalized NH-Pyrroles

Doi:10.1002/adsc.201900938
(2019)

Article Doi