A convenient one-pot synthesis of 6-trifluoromethyl-pyridines

DOI: 10.3987/com-98-8102

Source and publish data:

Heterocycles p. 779 - 785 (1998)

Update date:2022-08-03

Topics:

Authors:

Katsuyama, Isamu

Ogawa, Seiya

Nakamura, Hiroko

Yamaguchi, Yoshihiro

Funabiki, Kazumasa

Matsui, Masaki

Muramatsu, Hiroshige

Shibata, Katsuyoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/com-98-8102

α,β-Unsaturated trifluoromethyl ketones (1) react with primary enamines (2) such as β-aminocrotononitrile and β-aminocrotonates in the presence of phosphorus oxychloride / pyridine adsorbed on silica gel and manganese dioxide, providing good to high yield

Full text of DOI:10.3987/com-98-8102

Products guided by the article

Product name:3-cyano-1,4-dihydro-2-methyl-4-phenyl-6-trifluoromethylpyridine

Cas No:200879-84-1

R&D Labs maybe for 200879-84-1

China Synchem Technology Co.,Ltd

website:http://www.cnsynchem.com

Contact:+86-0552-4929311

Address:No.217 Daqing Road
Kaymossy BioChem Tech Co., Ltd

website:http://www.kaimosi.com

Contact:0571-87191913/0571-87199097

Address:Room 215, Building 3rd, No.288 Ningxia Road, Qingdao city, China
Shanghai Kangxin Chemical Co., Ltd

Contact:+86 21 60717227

Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai
Tomo Pharma Chem Co., Limited

Contact:+86-158-05817090

Address:ROOM 9F, FLAT 2, GUODU DEVELOPING BLDG, No.182, ZHAOHUI ROAD
xuri chemicals co., ltd

Contact:86-516-66656369

Address:The west road of Huaihai, Xuzhou, China

Relevant to this article

Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors

Doi:10.1021/jm4007774
(2013)
Enzymatic reduction of acetophenone derivatives with a benzil reductase from Pichia glucozyma (KRED1-Pglu): electronic and steric effects on activity and enantioselectivity

Doi:10.1039/c6ob00047a
(2016)
Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)- 1-phenylethanol derivatives

Doi:10.1016/j.ejmech.2012.01.034
(2012)
REACTION OF BENZYL CHLORIDE WITH PROPYLENE AND TRIFLUOROPROPENE UNDER METALLOCOMPLEX INITIATION CONDITIONS

Doi:10.1007/BF00961302
(1991)
On the Lewis acid-catalysed reaction of the 2,3-bis(trimethylstannyl)-1-alkene moiety with aldehydes

Doi:10.1016/0022-328X(91)86010-N
(1991)
β,β,β-Trichloroethyl-NH-Enamine as Viable System for 5-Endo-trig Radical Cyclization via Multifaceted Cu^I?Cu^II Redox Catalysis: Single Step Synthesis of Multi-Functionalized NH-Pyrroles

Doi:10.1002/adsc.201900938
(2019)

Article Doi