A convenient one-pot synthesis of 6-trifluoromethyl-pyridines

DOI: 10.3987/com-98-8102

Source and publish data:

Heterocycles p. 779 - 785 (1998)

Update date:2022-08-03

Topics:

Authors:

Katsuyama, Isamu

Ogawa, Seiya

Nakamura, Hiroko

Yamaguchi, Yoshihiro

Funabiki, Kazumasa

Matsui, Masaki

Muramatsu, Hiroshige

Shibata, Katsuyoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/com-98-8102

α,β-Unsaturated trifluoromethyl ketones (1) react with primary enamines (2) such as β-aminocrotononitrile and β-aminocrotonates in the presence of phosphorus oxychloride / pyridine adsorbed on silica gel and manganese dioxide, providing good to high yield

Full text of DOI:10.3987/com-98-8102

Products guided by the article

Product name:3-cyano-1,4-dihydro-2-methyl-4-phenyl-6-trifluoromethylpyridine

Cas No:200879-84-1

R&D Labs maybe for 200879-84-1

X.T.Y Environ-Tech Co.,Ltd

Contact:+86-310-7092106

Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
Tianjin Ji Ping Jia Chemical Co., Ltd.

Contact:18622448868

Address:tianjin
ShangHai BMG Chemical Co., Ltd

Contact:+86-13524845543

Address:Room 602, no 291 sikai road shanghai
Xiamen Kaijia Imp & Exp Co., Ltd.

Contact:86-592-5101177

Address:Room406 Luhui Building No. 65 Haitian Road Huli Xiamen,China.
Yancheng Smiling Imp & Exp Co., Ltd.

Contact:+86-515-83173586

Address:Rm1207, BLD#03, Phoenix Plaza, Juheng Road, Yancheng, Jiangsu, P.R. China

Relevant to this article

Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors

Doi:10.1021/jm4007774
(2013)
Enzymatic reduction of acetophenone derivatives with a benzil reductase from Pichia glucozyma (KRED1-Pglu): electronic and steric effects on activity and enantioselectivity

Doi:10.1039/c6ob00047a
(2016)
Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)- 1-phenylethanol derivatives

Doi:10.1016/j.ejmech.2012.01.034
(2012)
REACTION OF BENZYL CHLORIDE WITH PROPYLENE AND TRIFLUOROPROPENE UNDER METALLOCOMPLEX INITIATION CONDITIONS

Doi:10.1007/BF00961302
(1991)
On the Lewis acid-catalysed reaction of the 2,3-bis(trimethylstannyl)-1-alkene moiety with aldehydes

Doi:10.1016/0022-328X(91)86010-N
(1991)
β,β,β-Trichloroethyl-NH-Enamine as Viable System for 5-Endo-trig Radical Cyclization via Multifaceted Cu^I?Cu^II Redox Catalysis: Single Step Synthesis of Multi-Functionalized NH-Pyrroles

Doi:10.1002/adsc.201900938
(2019)

Article Doi