Bioorganic and Medicinal Chemistry Letters p. 3081 - 3084 (1997)
Update date:2022-09-26
Topics:
Hutchinson, Sally A.
Luetjens, Henning
Scammells, Peter J.
5-(3-Hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzo[b]furan-3 -carbaldehyde (XH-14, 1) has been reported to be a potent A1 adenosine antagonist. We have developed an efficient synthesis of this compound that should prove valuable for further structure-activity studies. The synthesis incorporates optimised methodology for the selective protection of a hydroxyl group and the ortho-bromination of a phenol.
View MoreSHANGHAI ARCADIA BIOTECHNOLOGY LTD.
Contact:+86-21-61353236
Address:SUITE 901, BUILDING WENSLI, 1378 LU JIA BANG RD, SHANGAHI 200011, P.R.CHINA
Chengda Pharmaceuticals Co., Ltd.
Contact:+86-573-84601188
Address:hengshan Road 5# in Jiashan, zhejiang
Wuxi D-Stone International Co., Ltd.
Contact:+86-510-82740567
Address:21F Hengtong Int'l Centre, 215Zhongshan Road, Wuxi, Jiangsu,China
website:http://www.sdowchem.com
Contact:86-135-2193 7483
Address:8-106 taiyue building
Jinan Trio PharmaTech Co., Ltd
Contact:86-531-88811783；+(0)13153010282
Address:2766 Yingxiu Road, Jinan High-Tech Zone, China
Doi:10.1021/ja016213l
(2001)Doi:10.1016/j.ica.2013.01.012
(2013)Doi:10.1016/S0960-894X(97)10189-5
(1998)Doi:10.1007/BF02546203
(1995)Doi:10.1021/jm00384a010
(1987)Doi:10.1021/ja01165a039
(1950)
