Bioorganic and Medicinal Chemistry Letters p. 3081 - 3084 (1997)
Update date:2022-09-26
Topics:
Hutchinson, Sally A.
Luetjens, Henning
Scammells, Peter J.
5-(3-Hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzo[b]furan-3 -carbaldehyde (XH-14, 1) has been reported to be a potent A1 adenosine antagonist. We have developed an efficient synthesis of this compound that should prove valuable for further structure-activity studies. The synthesis incorporates optimised methodology for the selective protection of a hydroxyl group and the ortho-bromination of a phenol.
View MoreHangzhou Hysen Pharma co.,Ltd.
website:http://www.hysenpharma.cn/
Contact:0086-571-88298791
Address:#701,Gudun Road Hangzhou
Shanxi Tongji Pharmaceuticals Co., Ltd.
Contact:+86-359-3024784
Address:Xikuang South Road, Ruicheng County , Shanxi
Contact:+86+21-58956006 15800617331
Address:402 Room, 150# Cailun Road, Zhangjiang high tech park, Shanghai
Liaoning Yufeng Chemical Co.,Ltd.
Contact:86-0419-3418888
Address:The metallurgical industrial zone,shoushan town, Liaoyang, Liaoning, China
Contact:+49-9398-993127
Address:Untertorstr. 27
Doi:10.1021/ja016213l
(2001)Doi:10.1016/j.ica.2013.01.012
(2013)Doi:10.1016/S0960-894X(97)10189-5
(1998)Doi:10.1007/BF02546203
(1995)Doi:10.1021/jm00384a010
(1987)Doi:10.1021/ja01165a039
(1950)
